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Esketamine is the S-enantiomer of ketamine. The FDA approved it in March of 2019 for treatment-resistant depression, when used in conjunction with an oral antidepressant (SSRI). The FDA recommended approval after reviewing five Phase III trials, of which two showed significant positive effects with moderate efficacy. Individuals recognize the substance for its rapid action in reducing depression and suicidal ideation. This relief becomes visible within four to 72 hours, and lasts up to several weeks. Buy S ketamine Esketamine For Sale
The evolution of esketamine
Buy S ketamine Esketamine For Sale is a mixture of two mirror-image molecules: “R” ketamine and “S” ketamine. As an off-label treatment for depression, it’s given intravenously, as an infusion into the bloodstream.
Esketamine, on the other hand, only contains the “S” ketamine molecule. As an FDA-approved treatment for persistent depression, it comes in the form of a nasal spray.
Spravato is the brand-name of the esketamine nasal spray that was approved by the FDA in March of 2019. It’s the first treatment of its kind, and the only NMDA receptor antagonist that’s FDA-approved for the treatment for persistent depression in adults.
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When the FDA announced that it was approving a fast-acting nasal spray for the treatment of persistent depression in adults, many people who had been living with TRD felt hopeful — and rightfully so — for the first time in years.
But this doesn’t mean you can simply get a prescription for Spravato and pop over to your local pharmacy and pick it up. When the FDA approved esketamine to treat major depression, it also provided strict guidance on exactly how the medicine should be administered.
That’s because, besides its immediate cognitive and mood-enhancing effects, ketamine can have sedating and dissociative effects. In fact, that’s why ketamine became a relatively popular recreational substance among partygoers in the 1990s.
Because of the adverse risks of sedation and dissociation as well as the potential for misuse, Spravato is only available through a restricted distribution system under a Risk Evaluation and Mitigation Strategy (REMS).
What does this mean for you? It means that, even though ketamine is self-administered, it must be taken under the guidance of an experienced physician in an authorized medical office.
A ketamine-certified treatment center
Here at Bespoke Treatment, we’re proud to be the first clinic in southern California to provide ketamine infusion therapy as well as Spravato esketamine nasal spray treatments for qualified patients.
Even though it only takes a moment to adminster Spravato, each esketamine treatment lasts about two hours from start to finish. Most of this time is spent monitoring your reaction to the medicine, to ensure you’re safe if you experience any mild hallucinations, dizziness, or vertigo.
Because you won’t be able to drive until the next day following a good night’s rest, you can only receive Spravato if you’ve arranged for someone else to drive you to and from your treatment.
If you suffer from persistent depression, we can help. Call your nearest Bespoke Treatment office in Los Angeles or Santa Monica, California, today, or click online to book an appointment with one of our experienced ketamine experts any time.